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Posts Tagged ‘fracture’

The disease
Osteoporosis is a diffuse disease of the skeleton characterized by decreased bone mass and impaired micro-architecture of bone tissue, causing a weakening of the bones and an increased risk of fracture. It can reach all the bones and remains asymptomatic in the absence of fracture.

Pathophysiology
Postmenopausal osteoporosis is promoted by estrogen deficiency. Other forms occur in the elderly of both sexes (formerly known as “senile osteoporosis”). Others are drug or endocrine origin (long-term steroid therapy, hyperthyroidism, hypogonadism, etc..). Read the rest of this entry »